The Hamilton PRP-1 phases are polymer phases based on polystyrene / divinylbenzene. PRP-1 columns are mainly used in reversed-phase chromatography. They are stable over the entire pH range (0-14). Often, polymer phases have better recovery rates for all analytes than silica-based reverse phases. The Hamilton PRP-1 materials also have chemical stability to all aqueous and organic solvents. The filling materials are available in columns with 11 different inside diameters from 1 mm to 101.6 mm, both in stainless steel and in PEEK. Precolumns are available for analytical, semi-preparative and preparative use.