COLUMN OVEN / COLUMN THERMOSTAT VARIOTHERM 4110

For UHPLC / UPLC / HPLC / LC - COLUMN SWITCH / COLUMN SELECTION - FROM 5 to 90° C

COLUMNOVEN 4110
BISCHOFF VARIOTHERM 4110
- 5 – 90°C
- Temperature gradient
programming
- Excellent temperature
stability
- Integrated solvent pre-heater
- Vapour sensor
- Automated column selection
Almost every parameter defining a chromatographic separation is temperature dependent. Suffice it to say that temperature control provides an indispensable tool to optimize your HPLC or UHPLC assay. As you will easily recognize, retention times will be more constant with constant temperature, but varying the temperature can also be a great help to tune selectivity, improve peak shape and reduce analysis time. Plus, high temperatures reduce column back pressure significantly, allowing higher solvent flow rates, narrower columns or smaller particles. Clearly, such benefits will only come true if the temperature itself is stable and precise, and without temperature gradients in the oven or the column. And this is exactly what we had in mind when we designed the VARIOTHERM with its forced air oven, excellent temperature control and integrated solvent pre-heater.
Automated column selection
Select up to 6 different columns via
the keyboard or the PC! This feature
comes as an option and will be a
great help for method development
or if you want to run multiple assays
on a single system. UHPLC valve
available!

Reduce acetonitrile use!
Higher column temperatures allow lower acetonitrile content in the
mobile phase for the same separation or may even allow the use of
methanol instead. An easy way to save on acetonitrile!

Specifications

Parameter

value

conditions

Temperature range

5°C - 90°C, with 1°C increments

5°C - 75°C, with 1°C increments,

if optional Column Selection Valve

is installed

Ambient temperature and humidity influence the lower temperature limit of the VARIOTHERM Typically, a ΔT of 18°C is feasible.

Temperature accuracy

Better than 0.1°C

Measured at 30°C in the centre of the oven compartment

Temperature stability

Better than 0.1°C

Measured at 30°C in the centre of the oven compartment

Temperature reproducibility

Better than 0.1°C

In the centre of the oven compartment

Temperature gradient

Better than 0.2°C

Measured in the column area

Temperature change

Up: 10°C/min from 40° to 60°C

Down: 2°C/min from 60°C to 40°C

Time programmable temperature

change

Time base: 9hr59 total time with

1-minute increments

Maximum 10 programmable steps

Programmable temperature ramp

Up: 0.1 – 5.0°C/min

Down: 0.1 – 1.5°C/min (75°C to

25°C)

It is possible to program a ramp

up to 9.9°C/min; however, only

the ramp ranges specified can be

guaranteed for the actual temperature

ramp.

Dimensions (H x W x D)

600 x 170 x 345 mm (h x w x d)

Weight

16 kg

Working Environment

5 - 40°C; 30 - 80% RH

Power Requirements

115/230 VAC +15/-22%,; 50/60 Hz

Power consumption

454 VAmax

Column selection Valve

1-to-6 port high pressure solvent selection valve:

HPLC version standard

UHPLC 15,000 PSI version optional

Control

Keyboard

All functionality can be accessed and read trough the

integrated keyboard with display

Outputs:

Temperature or vapor alarm (relay + buzzer)

Relay contacts: Vmax = 28 Vdc/Vac, Lmax = 0.25A

Oven ready (relay), will be activated if the actual tempe- Lmax = 0.25A

rature is within 0.5°C of the set point temperature.

Inputs:

Start temperature program (TTL)

TTL inputs are active low and must be low for at least 1 second.

Emergency shut-down (TTL)

PC interface

RS 232 is standard.

USB or Ethernet possible on request.

A MultiLink output connector

allows linking of RS 232 communication

to other instruments

Firmware updates can be uploaded

via RS 232

SparkLink 4.0 software allows control

of main VARIOTHERM functions

from a PC.

VARIOTHERM COOL
P/N 4110 0000
VARIOTHERM COOL with COLUMN SELECTION
P/N 4110 0020
VARIOTHERM without COOL
P/N 4110 0030
VARIOTHERM without COOL with COLUMN SELECTION
P/N 4110 0040